Primary Skin Irritation Test (Mandatory SIAA test item)
This test verifies the presence of dermal reactions from the test substance on the skin of the test animals by making a slight scar on the skin of the test animals, and smearing the test substance onto this site.
The objective of this test is to determine the toxicity upon a single application of the test substance onto the scarred tissue of the test animal from both the qualitative and quantitative (lethal dose) aspects.