Rat Sub-chronic Toxicity Test
The objective of this test is to examine the occurrence of toxic reactivity from a test substance when it is administered repeatedly to a test animal for a relatively short period (3 months). In this test, the quantity of a test substance causing obvious toxicity (toxic dose) and the quantity of a test substance producing no effect (non-toxic dose) are also identified to understand the full toxicity level of a test substance.
Checks in the test animals’ medical states, weight, feed intake, and such are monitored. After anatomical dissection, each of their organs are checked for biologic reactions.